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Trials designed to inform clinical practice in the real world are known as pragmatic trials. They are often characterized by a focus on the practical aspects of the research design, like recruitment and consent as well as adherence to the use of commonly available equipment.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which used various investigators and had participants from different geographic areas. This kind of heterogeneity is necessary for pragmatic trials to be valid and reduces bias in the results. However excessive heterogeneity could cause issues with the design of the trial.

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The goal of pragmatic trials is to mimic real-life situations and achieve maximum credibility externally. They are usually requested by practitioners and policymakers to inform their decisions. They are also a good method of determining the causal relationship between an intervention and its outcomes. However, they should not, be used to replace explanation studies.

The pragmatism concept is controversial and there are concerns about whether pragmatic trials should replace explanatory trials or 무료프라그마틱 슬롯 환수율 프라그마틱 추천 (Https://btpars.Com/Home.Php?mod=space&uid=3912994) complement them. Schwartz and Lellouch1 made a distinction between explanatory studies, which prove a physiological hypothesis or clinical hypothesis, as well as pragmatic trials that aid in the practice and policy decision-making. They also proposed a framework called PRECIS for pragmatic trials.2 This tool attempted to define the characteristics of a pragmatic study which includes the recruitment, 프라그마틱 슬롯무료 design, and delivery of the intervention and its follow-up.

The number of pragmatic trials is increasing. A recent Medline query using the keywords pragmatic and naturalistic, limited to randomised controlled trials (RCTs) returned 34 articles. These are highlighted in red on Figure 2. This is a sign that the health sciences community is becoming more acquaint to the subject of pragmatism. It is important to keep in mind that the majority of studies were conducted in primary-care settings.