ADHD Medication During Pregnancy and Breastfeeding
The choice of whether to stop or continue ADHD medication during pregnancy and breastfeeding is challenging for women with the condition. There is a lack of information about how long-term exposure to these drugs can affect the foetus.
A recent study published in Molecular Psychiatry demonstrates that children exposed to ADHD medication during pregnancy do not develop neurological disorders such as hearing loss or vision, febrile seizures or IQ impairment. The authors acknowledge that more high-quality research is needed.
Risk/Benefit Analysis
Pregnant women who use ADHD medications must weigh the advantages of using them against the risks to the foetus. Doctors don't have the information needed to make unequivocal recommendations however they can provide information regarding the risks and benefits to aid pregnant women in making informed decisions.
A study published in Molecular Psychiatry concluded that women who were taking ADHD medication in early pregnancy were not at a higher risk of fetal malformations or structural birth defects. Researchers conducted a massive population-based study of case control to compare the incidence of major structural defects in infants who were born to mothers who took stimulants during pregnancy. Pediatric cardiologists and clinical geneticists examined the cases to ensure an accurate case classification and to minimize the chance of bias.
However, the study was not without its flaws.
most effective adhd medication important, they were unable to separate the effects of the medication from the underlying disorder. This limitation makes it difficult for researchers to determine whether the few associations observed between the groups that were exposed to the use of medication or if they were caused by the presence of comorbidities. In addition the researchers did not study the long-term effects of offspring on their parents.
The study did reveal that infants whose mothers had taken ADHD medication during pregnancy were at slightly more risk of being admitted to the neonatal intensive care unit (NICU) than infants whose mothers had not taken any medication or had taken off their medication prior to or during pregnancy. The reason for this was central nervous system disorders. The higher risk of admission was not affected by the stimulant medication used during pregnancy.
Women who were taking stimulant ADHD medications during pregnancy also had a higher risk of having to have a caesarean section or a baby that scored low on the Apgar scale (less than 7). These increases didn't appear to be influenced by the kind of medication used during pregnancy.
Researchers suggest that the minor risks associated with the use ADHD medications during early pregnancies
can a general practitioner prescribe adhd medication be offset by more beneficial outcomes for both mother and baby of continuing treatment for the woman's condition. Physicians should talk to their patients about this and as much as possible, assist them develop coping skills that can lessen the impact of her disorder in her daily functioning and her relationships.
Medication Interactions
More and more doctors are confronted with the dilemma of whether to maintain treatment or stop as more women are diagnosed with ADHD. These decisions are often made without clear and authoritative evidence. Instead, doctors have to weigh their own knowledge and experience, as well as the experiences of other physicians and the research on the topic.
The issue of possible risks for infants can be particularly tricky. A lot of studies on this issue are based on observational data rather than controlled research, and their findings are often contradictory. Most studies restrict their analysis to live births, which can underestimate the teratogenic impact which can cause terminations or abortions of pregnancy. The study presented in this journal club addresses these issues by analyzing data on live and deceased births.
Conclusion A few studies have revealed a positive correlation between ADHD medications and certain birth defects, other studies have not established a link. Most studies show a neutral, or even slight negative impact. In the end, a careful risk/benefit assessment must be conducted in every instance.
For women suffering from ADHD, the decision to stop medication is difficult, if not impossible. In a recent article published in the Archives of Women's Mental Health by psychologist Jennifer Russell, she notes that stopping
adhd focus medication medications during pregnancy can increase depression and feelings of isolation. The loss of medication can affect the ability to safely drive and perform work-related tasks, which are essential aspects of normal life for those with ADHD.
She suggests women who are unsure about whether or not to discontinue medication due to their pregnancy should consider the possibility of educating friends, family members and colleagues about the condition, its impact on daily functioning, and on the advantages of staying on the current treatment plan. Educating them can also help the woman feel supported as she struggles with her decision. It is also worth noting that certain drugs can pass through the placenta so if the patient decides to stop her ADHD medication during pregnancy and breastfeeding, she should be aware that the effects of the drug could be transferred to the child.
Risk of Birth Defects
As the use of ADHD drugs to treat symptoms of attention deficit hyperactivity disorder (
adhd medications for adults With anxiety) grows, so do concerns about the effects that the drugs might have on fetuses. Recent research published in the journal Molecular Psychiatry has added to the body of knowledge on this subject. Utilizing two huge data sets, researchers were able to examine more than 4.3 million pregnancies to determine whether stimulant medication use increased the risk of birth defects. Researchers discovered that although the overall risk is low, first-trimester ADHD exposure to medication was associated with slightly higher risk of certain heart defects, like ventriculoseptal defect.
The researchers of the study didn't find any association between the use of early medications and other congenital anomalies like facial deformities or club feet. The results are in line with previous studies that have shown the presence of a small, but significant increase in the risk of heart malformations among women who began taking ADHD medications prior to the time of pregnancy. The risk grew during the latter part of pregnancy, when a lot of women are forced to stop taking their ADHD medications.
Women who were taking
starting adhd medication adults medication in the first trimester were more likely require a caesarean birth and also have a low Apgar after delivery, and have a baby that needed breathing assistance after birth. The researchers of the study were unable to eliminate bias due to selection because they limited the study to women without other medical conditions that could have contributed to the findings.
Researchers hope that their research will help doctors when they encounter pregnant women. They recommend that, while the discussion of the benefits and risks is important however, the decision to stop or keep medication should be based on each woman's requirements and the severity of her ADHD symptoms.
The authors caution that, while stopping the medication is a possibility to look into, it is not recommended because of the high incidence of depression and other mental problems in women who are expecting or who have recently given birth. Additionally, research suggests that women who stop taking their medication will have a harder time adjusting to a life without them once the baby is born.
Nursing
The responsibilities of being a new mother can be overwhelming. Women suffering from ADHD can face severe challenges when they must manage their symptoms, attend doctor appointments and prepare for the birth of a child and adjust to new routines. As such, many women elect to continue taking their ADHD medications throughout pregnancy.
The risk to a breastfeeding infant is not too high since the majority of stimulant medications is absorbed through breast milk at low levels. However, the frequency of exposure to medications by the infant can differ based on dosage, how often it is administered, and the time of day it is administered. Additionally, individual medications enter the infant's system differently through the gastrointestinal tract as well as breast milk and the impact of this on a newborn infant is not fully understood.
Due to the absence of research, some physicians might be tempted to stop taking stimulant drugs during the course of pregnancy. This is a difficult decision for the woman who must weigh the advantages of her medication against the potential risks to the foetus. In the meantime, until more information is available, doctors can ask pregnant patients whether they have an background of ADHD or if they plan to take medication in the perinatal stage.
A increasing number of studies have proven that women can continue their ADHD medication during pregnancy and while breastfeeding. This has led to many patients choose to do so and, in consultation with their doctor they have found that the benefits of continuing their current medication outweigh any potential risks.
Women with ADHD who are planning to nurse should seek the advice of an expert psychiatrist prior to becoming pregnant. They should discuss the medication they are taking with their physician and discuss the pros and cons for continuing treatment. This includes non-pharmacological strategies. Psychoeducation is also required to help pregnant women suffering from ADHD be aware of the symptoms and underlying disorder. They should also be informed about treatment options and reinforce strategies for coping. This should include a multidisciplinary approach, which includes the GP, obstetricians and psychiatry. Pregnancy counseling should include a discussion of a treatment plan for the mother as well as the child, monitoring of indicators of deterioration, and, if necessary adjustments to the
medication for inattentive adhd regime.